| Publication Type: | Journal Article |
| Year of Publication: | 2002 |
| Authors: | K. Okazaki, Kawazoe, K., Takaishi, Y. |
| Journal: | Phytotherapy Research |
| Volume: | 16 |
| Issue: | 4 |
| Pagination: | 398 - 399 |
| Date Published: | 2002/06// |
| Abstract: | Two antiaggregant compounds, thymol (compound 1) and 3,4,3',4'-tetrahydroxy-5,5'-diisopropyl-2,2'-dimethylbiphenyl (compound 2) were isolated from the leaves of thyme (Thymus vulgaris L.). The structures were determined by H-1-, C-13-NMR and mass spectra (MS) studies. These compounds inhibited platelet aggregation induced by collagen, ADP, arachidonic acid (AA) and thrombin except that compound 2 did not inhibit platelet aggregation induced by thrombin. Copyright (C) 2002 John Wiley Sons, Ltd. |
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