01601nas a2200181   4500008004100000020001400041245008500055210006900140260001200209300001400221490000700235520095100242100001101193700001501204700002101219700001701240856016201257       2006                        eng d  a1388-020900aComposition and Antimicrobial Activity of the Essential Oil of Thymus fontanesii0 aComposition and Antimicrobial Activity of the Essential Oil of T  c2006///  a607 - 6120 v443 aThe yield of oil isolated by hydrodistillation from aerial parts of Thymus fontanesii Boiss. et Reut. (Lamiaceae) growing wild in Djelfa (Algeria) was 0.9%. Analysis of the oil by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS) revealed the identification of 47 components accounting for 98.5% of the total oil. The oil was found to be rich in monoterpenes (91.5%) with major constituents being thymol (29.3%), gamma -terpinene (21.7%), p-cymene (15.9%), and thymol methyl ether (11.4%), while a smaller amount of linalool (4.8%) and beta -caryophyllene (2.9%) were detected. According to the antimicrobial study using the disk diffusion method and the agar dilution assay-minimal inhibitory concentration (MIC), the oil showed strong in vitro growth inhibition activity against Gram-negative bacteria and antifungal activity. The oil exhibited the maximum antifungal activity against Mucor ramaniamus (MIC = 0.2 mu L/mL)1 aDob, T1 aDahmane, D1 aBenabdelkader, T1 aChelghoum, C  uhttp://muse.lib.auth.gr:9797/com/csa/?MuseHost=www-mi2.csa.com&MuseFirst=1&id=2&recnum=0&SID=147874bda29087943ea1dc03733c75de&MusePath=/ids70/view_record.php