02305nas a2200181   4500008004100000245015600041210006900197260027900266300001000545490000700555520135400562100001801916700001901934700001901953700002001972700001401992856011702006       2011                        eng d00aChemical composition, larvicidal evaluation, and adult repellency of endemic Greek Thymus essential oils against the mosquito vector of West Nile virus0 aChemical composition larvicidal evaluation and adult repellency   aAffiliation: Department of Pharmacognosy and Chemistry of Natural Products, School of Pharmacy, University of Athens, Panepistimioupoli Zographou, Athens, 157 71, Greece; Affiliation: Department of Entomology and Agricultural Zoology, Laboratory of AgricubSpringerc2011///  a1 - 60 v213 aThe volatile metabolites of Greek wild growing Thymus leucospermus and Thymus teucrioides subsp. candilicus were determined by gas chromatography and gas chromatography-mass spectrometry. The monoterpene hydrocarbon p-cymene (64.2%) dominated T. leucospermus oil, followed by γ-terpinene (7.9%), thymol (4.8%), and borneol (4.7%), whereas the most abundant constituents in T. teucrioides subsp. candilicus oil were p-cymene (25.5%), γ-terpinene (19.0%), thymol (18.8%), borneol (5.7%), and α-pinene (5.7%). The larvicidal and repellent activities of the analyzed essential oils were tested on Culex pipiens larvae and adults, respectively. Additionally, the main metabolite of the essential oils, p-cymene was tested against C. pipiens adults in order to define the affiliation between p-cymene and the repellent properties of the oil. The essential oils of T. leucospermus and T. teucrioides subsp. candilicus provided repellency 78.1% and 72.9%, respectively, statistically equal to the reference product icaridin. The compound p-cymene showed almost no repellent activity. The essential oil of T. leucospermus presented lower larvicidal activity (LC50 = 34.26 mgl-1) against C. pipiens third-fourth instar larvae while T. teucrioides subsp. candilicus was the most active with an estimated LC50 value of 23.17 mgl-1. © 2011 Springer-Verlag.1 aPitarokili, D1 aMichaelakis, A1 aKoliopoulos, G1 aGiatropoulos, A1 aTzakou, O  uhttp://www.scopus.com/inward/record.url?eid=2-s2.0-79551599553&partnerID=40&md5=9529f7b437953253909c1eb26a181550