02155nas a2200265   4500008004100000245009900041210006900140260026900209300001200478490000700490520108100497653002401578653003001602653001301632653001101645653002001656653001901676100001801695700002001713700001401733700001701747700001301764700001501777856009701792       2004                        eng d00aChemical composition and fungicidal activity of commercial essential oils of Thymus vulgaris L0 aChemical composition and fungicidal activity of commercial essen  aAffiliation: DPVA, Via Filippo Re 8, 40126 Bologna, Italy; Affiliation: DMPOB, Viale Caduti in Guerra, 127, 41100 Modena, Italy; Affiliation: Dipto. di Scienze Farmaceutiche, Via Campi 183, 41100 Modena, Italy; Affiliation: Ist. Biologia Evolutiva Funzionc2004///  a69 - 740 v163 a<p>The antifungal activity of commercial Thymus vulgaris oils on the development of mycelium of the phytopathogenic fungi Fusarium solani (Mart.) Sacc., Rhizoctonia solani Kühn and Colletotrichum lindemuthianum (Sacc. et Magn.) Briosi et Cav. was studied. The gas chromatography data showed that the essential oils were rich in thymol (22-38%) and its biogenetic precursors &gamma;-terpinene and p-cymene. The carvacrol content was relatively low in all the oils tested, ranging between 1% and 2%. The fungicidal activity of the oils was correlated with their thymol content. The principal chemical components of thyme oils were then tested using the same concentrations as in the thyme oils. Only the fungicidal activity of thymol was high and close to that of the oils with the same thymol content. The effects of the thyme oils and thymol on the hyphae cytomorphology of the studied fungi was an increased vacuolization of the cytoplasm and accumulation of lipid bodies, undulations of the plasmalemma, and alterations of the mitochondria and endoplasmic reticulum.</p>
10aAntifungal activity10aEssential oil composition10aLabiatae10aThymol10aThymus vulgaris10aUltrastructure1 aZambonelli, A1 aD'Aulerio, A, Z1 aSeveri, A1 aBenvenuti, S1 aMaggi, L1 aBianchi, A  uhttp://www.scopus.com/scopus/inward/record.url?eid=2-s2.0-1242310478&partnerID=40&rel=R6.5.0